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Postdoctoral studies in developmental lineage tracing of the brain and choroid plexus (scholarship)
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Login and apply Do you want to contribute to top quality medical research? Join the Andersson Lab at Karolinska Institutet to uncover how the embryonic brain and choroid plexus are formed. We combine pioneering in utero nano-injection methods with genetic barcoding, single-cell sequencing and advanced imaging to trace cell lineages directly in developing mouse embryos. The successful candidate will help establish a new framework for understanding the developmental origins, diversification, and organization of the choroid plexus in relation to surrounding neural tissues, in a collaborative and internationally connected research environment. Division The Andersson Lab is based at the Department of Cell and Molecular Biology (CMB), Karolinska Institutet, at BioMedicum in Stockholm. Our research focuses on mammalian developmental biology and regenerative medicine, with a particular emphasis on lineage tracing and genetic manipulation of early progenitor populations. We have developed in utero nano-injection approaches for delivering lentiviral vectors to embryonic tissues, enabling prospective lineage tracing and cell-type-specific manipulation across the developing nervous system and other organs. We integrate these tools with single-cell transcriptomics, molecular analysis, and three-dimensional imaging to understand how cellular diversity and tissue architecture arise. Duties The postdoctoral project will investigate the developmental lineage relationships between the choroid plexus and neighboring brain territories, including the origin, diversification, and spatial organization of choroid plexus epithelial and associated cell populations. The candidate will use early in utero nano-injection and barcode lineage tracing to resolve cell lineages. The duties will include experimental planning and optimization of embryonic targeting, collection and characterization of developing tissues, immunofluorescence and microscopy, and preparation of samples for single-cell RNA sequencing and barcode recovery. Interacting with computational collaborators, the candidate will interpret cell identities, lineage relationships, and developmental trajectories, and integrate these findings with tissue anatomy and spatial information. The position also involves presenting research, preparing manuscripts, contributing to collaborative projects, and participating actively in the laboratory research environment. Entry requirements We seek a motivated and independent researcher with a PhD in developmental biology, cell biology, neuroscience, molecular biology, or a closely related field. Required qualifications: A strong background in embryonic brain development and/or choroid plexus biology is particularly relevant. Practical experience with mouse embryonic tissues (FELASA certification is meriting). Practical experience with developmental phenotyping, molecular biology and imaging. A demonstrated ability to plan and conduct rigorous experiments. Excellent communication skills in English. Ability to work collaboratively are required. Experience with choroid plexus morphogenesis, epithelial development, neural progenitor biology, immunofluorescence, confocal microscopy, or analysis of developmental signalling pathways is particularly advantageous. Experience with in vivo genetic manipulation, lentiviral methods, single-cell transcriptomics, or lineage tracing is desirable, but training in these techniques will be provided. We value scientific curiosity, careful experimental work, initiative, and enthusiasm for learning new approaches. Postdoctoral scholarships may be established for foreign researchers who pursue their merit in Sweden. A foreign researcher is a person living in another country who comes to Sweden with the intention of only staying in Sweden for all or part of their postdoctoral education at KI. Persons who are resident in Sweden and/or have carried out all or part of their academic education at KI or some other educational institution in Sweden cannot be considered for scholarships. The purpose of scholarships for postdoctoral qualification is to promote internationalization and contribute to research qualification after a doctorate or equivalent. A scholarship for carrying out postdoctoral research can be granted for a maximum of two years within a four-year period following the receipt of a doctoral degree or equivalent. To be eligible for a postdoctoral scholarship, the person must have obtained a doctorate, or a foreign degree deemed to be equivalent to a doctorate. Applicants who have not completed a doctorate at the end of the application period may also apply, provided that all requirements for a completed degree are met before the (intended) start date of the post-doctoral education. What do we offer? A creative and inspiring environment with wide-ranging expertise and interests. Karolinska Institutet is one of the world's leading medical universities. Here, we conduct innovative medical research and provide the largest range of biomedical education in Sweden. At KI, you get to meet researchers working with a wide range of specialisms and methods, giving you ample opportunity to exchange knowledge and experience with the various scientific fields within medicine and health. It is the crossover collaborations, which have pushed KI to where it is today, at the forefront of global research. Several of the people you meet in healthcare are educated at KI. A close relationship with the health care providers is important for creating groundbreaking top quality education and research. Students and employees have free access to our modern gym facilities with trained staff on site. Location: Type of scholarship The amount is tax free and it is set for twelve months at a time, paid out on a six months basis. In exceptional cases, shorter periods may be acceptable. Application process An application must contain the following documents in English or Swedish: A complete curriculum vitae, including date of the thesis defence, title of the thesis, previous academic positions, academic title, current position, academic distinctions, and committee work A complete list of publications A summary of current work (no more than one page) The application is to be submitted on the Varbi recruitment system. Want to make a difference? Join us and contribute to better health for all First day of employment Upon agreement Salary Scholarship Reference number STÖD 2-4608/2026 Published 12.Nov.2026 Last application date 02.Dec.2026 Login and apply Share links Return to job vacancies