Genomics England
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Genomics England is a global leader in enabling genomic medicine and research, focused on creating a world where everyone benefits from genomic healthcare. Building on the 100,000 Genomes Project, we support the NHS’s world-first national whole genome sequencing service and run the growing National Genomic Research Library, alongside delivering numerous major genomics initiatives. By connecting research and clinical care at national scale, we enable immediate healthcare benefits and advances for the future.
Our mission is to provide the evidence and digital systems so that by 2035 genomics could play a role in up to half of all healthcare interactions, whilst securing the UK’s position as the best place to discover, prove and benefit from genomic innovations.
We are accelerating our impact and working with patients, doctors, scientists, government and industry to improve genomic testing, and help researchers access the health data and technology they need to make new medical discoveries and create more effective, targeted medicines for everybody.
Behind the Healthcare and Research outcomes, Genomics England delivers through designing, developing and operating complex healthcare software systems.
We're on the cusp of big changes with the real prospect of genomics becoming the fabric of everyday healthcare through the lifetime - from birth to old age.
Senior Technical Product Manager
Every genome sequenced through the NHS Genomic Medicine Service has to pass through complex bioinformatics workflows before it becomes a result a clinician can act on. Genie is the product that makes that happen.
Genie is our Nextflow-native workflow orchestrator. We built it in-house, and it now launches, runs and tracks the bioinformatics workflows behind the whole genome sequencing tests we provide to the NHS for rare disease and cancer, as well as national programmes such as the Generation Study, which is sequencing newborns' genomes to look for more than 200 rare genetic conditions. Those workflows form part of our regulated medical device. Genie is how they run, reliably and at national scale.
Genie has been built, launched and adopted. Its next stage is different: making it operationally excellent, scalable and sustainable as a product that the NHS relies on every day. That means bringing new tests and workflow improvements into service faster, keeping turnaround and reliability where clinicians need them as demand grows, and improving the economics of running each test, including its compute cost, so that genomic medicine can reach more patients.
As Senior Product Manager for Genie, you'll own that direction. You'll start from the problems that matter most to Genie's users, to patients and to Genomics England, and lead a multi-disciplinary team to solve them in ways that create lasting value.
Why this role matters
Real patients, national scale. England's Genomic Medicine Service was the first national health system to offer whole genome sequencing as part of routine care. Throughput, turnaround time, reliability and cost per test are not abstract metrics here. They affect how quickly families get answers and how quickly clinicians can act.
A product entering a new stage of its life. The important questions for Genie are now about scale, operability, cost and sustainability, alongside new capability. Deciding which problems to solve, in what order, and which to leave alone is the heart of the job.
A clear line to national strategy. Genomics England's strategy, the NHS 10 Year Health Plan and the UK Life Sciences Sector Plan all place genomics at the centre of future healthcare. Genie is part of the infrastructure that makes those ambitions deliverable, so its direction matters well beyond one team.
Rigour that matters. Genie runs workflows that are part of a regulated clinical service. Quality, traceability and safe change matter as much as new features, and good product decisions here respect both.
What you'll be doing
Who you'll work with
You'll report to the Group Product Manager for Bio Pipelines. The role has no direct reports. You'll lead through influence, across a cross-functional team and a wide group of stakeholders: bio operations, bioinformatics workflow teams, engineering, user research, design, quality and regulatory, clinical and scientific leads, and NHS partners. They won't all want the same things from Genie, and helping them reach a shared view of what matters most is a large part of the role.
What success looks like after 12 months
Above all, you're a product manager in the truest sense. You get deeply interested in problems before you get attached to solutions, and you judge success by the value created for users and for the organisation, not by the volume of what was shipped.
You're curious. You ask sharp questions, you're comfortable saying “I don't know yet”, and you treat that as the start of finding out. You don't need to have every answer yourself. You know the best outcomes come from bringing the right people together, and you're the person who frames the problem, assembles that expertise and leads the group to a good decision.
You're grounded about technology. You understand technical systems well enough to engage credibly with engineers and scientists, and you choose tools because they solve the problem, not because they are new.
We're hiring for product management excellence first. If you can show that and you're excited by this role, please apply, even if you haven't worked in genomics or healthcare before. We'll help you learn the domain.
Why join us?
Few product roles have such a direct line between your decisions and patient care. Genie is part of the infrastructure behind a national genomic medicine service and studies that could shape the future of NHS newborn screening. You'll set its direction as it moves from newly built to essential, working with talented scientists and engineers in an organisation that is serious about its mission and practical about how it gets there.
Qualifications matter less to us than evidence of how you work. We're most interested in the depth of your product management practice: how you understand problems, create value for users and the organisation, lead technical products that others depend on, work with engineers, scientists and other disciplines, and bring clarity and direction to complex, ambiguous problems.
Additional Information
Closing date for applications: Thursday 26th November @ 23:00 (UK time)
Salary from: £76,000 per annum
Right to work: We are unable to offer visa sponsorship for this role.
Being an integral part of such a meaningful mission is extremely rewarding in itself, but in order to support our people, we’re continually improving our benefits package. We pride ourselves on investing in our people and supporting them to achieve their career goals, as well as offering a benefits package including:
Equal opportunities and our commitment to a diverse and inclusive workplace
Genomics England is actively committed to providing and supporting an inclusive environment that promotes equity, diversity and inclusion best practice both within our community and in any other area where we have influence. We are proud of our diverse community where everyone can come to work and feel welcomed and treated with respect regardless of any disability, ethnicity, gender, gender identity, religion, sexual orientation, or social background.
Genomics England’s policies of non-discrimination and equity and will be applied fairly to all people, regardless of age, disability, gender identity or reassignment, marital or civil partnership status, being pregnant or recently becoming a parent, race, religion or beliefs, sex or sexual orientation, length of service, whether full or part-time or employed under a permanent or a fixed-term contract or any other relevant factor.
Genomics England does not tolerate any form of discrimination, harassment, victimisation or bullying at work. Such behaviour undermines our mission and core values and diminishes the dignity, respect and integrity of all parties. Our People policies outline our commitment to inclusivity.
We aim to remove barriers in our recruitment processes and to be flexible with our interview processes. Should you require any adjustments that may help you to fully participate in the recruitment process, we encourage you to discuss this with us.
Culture
We have four key behaviours that represent what we would like Genomics England to feel like and the culture we want to encourage, in order for us to achieve our mission. These behaviours help us all work well together, deliver on our outcomes, celebrate our successes and share feedback with each other. You can read about these and other aspects of our culture here [Culture | Genomics England](https://www.genomicsengland.co.uk/careers/culture)
Blended working model
Genomics England operates a blended working model as we know our people appreciate the flexibility that hybrid working can bring. We expect most people to come into the office a minimum of 2 times each month. However, this will vary according to role and will be agreed with your team leader. There is no expectation that people will return to the office full time unless they want to, however, some of our roles require full time on site attendance e.g., lab teams, reception team.
Our teams and squads have, and will continue to reflect on what works best for them to work together successfully and have the freedom to design working patterns to suit, beyond the minimum. Our office locations are: Canary Wharf, Cambridge and Leeds.
Onboarding background checks
As part of our recruitment process, all successful candidates are subject to a Standard Disclosure and Barring Service (DBS) check. We therefore require applicants to disclose any previous offences at point of application, as some unspent convictions may mean we are unable to proceed with your application due to the nature of our work in healthcare.
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Source: Headcount Labs · original listing ↗
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